Cladribine an Alternative for Midostaurine in FLT3 Positive Acute Myeloid Leukemia

Midostaurin is registered for the indication newly diagnosed acute myeloid leukemia that is FLT3 mutation positive in combination with standard cytarabine and daunorubicine induction and cytarabine consolidation. The registration is based on a study of 717 patients that examined the addition of midostaurin 50 mg orally twice daily or placebo to standard induction on days 8 to 21 of a cycle for a maximum of two induction cycles.

Follow the link for full article
https://medwinpublishers.com/HIJ/HIJ16000134.pdf